Alan E Jones Selected Research

Lactic Acid (Lactate)

6/2021	Group IIA secretory phospholipase 2 independently predicts mortality and positive blood culture in emergency department sepsis patients.
12/2018	Effect of Levocarnitine vs Placebo as an Adjunctive Treatment for Septic Shock: The Rapid Administration of Carnitine in Sepsis (RACE) Randomized Clinical Trial.
1/2018	Phosphatidylserine expressing platelet microparticle levels at hospital presentation are decreased in sepsis non-survivors and correlate with thrombocytopenia.
12/2017	Clinical predictors of early death from sepsis.
10/2017	An Emergency Department Validation of the SEP-3 Sepsis and Septic Shock Definitions and Comparison With 1992 Consensus Definitions.
9/2017	The Impact of the Sepsis-3 Septic Shock Definition on Previously Defined Septic Shock Patients.
1/2016	Lactate Clearance in Septic Shock Is Not a Surrogate for Improved Microcirculatory Flow.
1/2016	Utilizing Geographic Information Systems to Identify Clusters of Severe Sepsis Patients Presenting in the Out-of-Hospital Environment.
12/2015	The effect of liver disease on lactate normalization in severe sepsis and septic shock: a cohort study.
10/2015	Plasma Glycoproteomics Reveals Sepsis Outcomes Linked to Distinct Proteins in Common Pathways.

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Alan E Jones Research Topics

Disease

60	Sepsis (Septicemia) 11/2021 - 08/2005
38	Septic Shock (Toxic Shock Syndrome) 01/2022 - 08/2005
21	Infections 02/2021 - 08/2007
14	Hypotension (Low Blood Pressure) 08/2020 - 01/2004
12	Inflammation (Inflammations) 01/2019 - 08/2007
12	Heart Arrest (Cardiac Arrest) 01/2019 - 04/2008
11	Pulmonary Embolism 01/2021 - 06/2003
9	Shock 09/2015 - 07/2007
4	Dyspnea (Shortness of Breath) 01/2019 - 03/2014
3	COVID-19 11/2022 - 01/2022
3	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 09/2017 - 04/2015
3	Acute Kidney Injury (Acute Renal Failure) 12/2016 - 03/2015
3	Neoplasms (Cancer) 09/2015 - 02/2011
3	Renal Insufficiency (Renal Failure) 05/2015 - 01/2010
3	Critical Illness (Critically Ill) 03/2015 - 05/2007
2	Venous Thromboembolism 01/2021 - 12/2017
2	Disseminated Intravascular Coagulation 08/2020 - 01/2018
2	Brain Injuries (Brain Injury) 01/2019 - 06/2010
2	Hyperlactatemia 01/2018 - 07/2013
2	Hyperoxia 01/2018 - 06/2010
2	Bacterial Infections (Bacterial Infection) 07/2016 - 09/2012
2	Ischemia 01/2016 - 01/2011
2	Liver Diseases (Liver Disease) 12/2015 - 02/2011
2	Chest Pain (Chest Pains) 05/2015 - 03/2014
2	Wounds and Injuries (Trauma) 10/2012 - 07/2011
2	Hypoxia (Hypoxemia) 06/2010 - 04/2010
1	Lung Injury 01/2022
1	Acute Lung Injury 01/2022
1	Enterobacteriaceae Infections 01/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2021
1	Urinary Tract Infections (Urinary Tract Infection) 01/2021
1	Edema (Dropsy) 10/2018
1	Thrombocytopenia (Thrombopenia) 01/2018
1	Necrosis 01/2017

Drug/Important Bio-Agent (IBA)

31	Lactic Acid (Lactate)FDA LinkGeneric 06/2021 - 08/2007
10	Carnitine (L-Carnitine)FDA LinkGeneric 11/2021 - 07/2013
8	Biomarkers (Surrogate Marker)IBA 12/2017 - 05/2009
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 09/2011
7	Oxygen (Dioxygen)IBA 10/2018 - 06/2010
4	ProcalcitoninIBA 06/2021 - 07/2007
3	Pharmaceutical PreparationsIBA 11/2021 - 01/2015
3	Carbon DioxideIBA 01/2019 - 09/2010
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 06/2014
3	Glucose (Dextrose)FDA LinkGeneric 12/2018 - 07/2009
3	fibrin fragment D (D-dimer)IBA 09/2010 - 11/2004
2	Complement System Proteins (Complement)IBA 08/2020 - 11/2010
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019 - 11/2003
2	Fatty Acids (Saturated Fatty Acids)IBA 12/2018 - 01/2018
2	Insulin (Novolin)FDA Link 01/2018 - 07/2009
2	HDL LipoproteinsIBA 01/2018 - 11/2017
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 10/2015
2	Tenecteplase FDA Link 08/2015 - 04/2007
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2013 - 09/2012
2	CreatinineIBA 06/2012 - 01/2010
2	E-SelectinIBA 08/2011 - 04/2010
1	AntibodiesIBA 11/2022
1	Nucleocapsid ProteinsIBA 02/2022
1	AntigensIBA 02/2022
1	Amino Acids FDA Link 01/2022
1	Losartan (Cozaar)FDA LinkGeneric 01/2022
1	Angiotensin IIIBA 01/2022
1	Protein Isoforms (Isoforms)IBA 06/2021
1	Phospholipases A2 (Phospholipase A2)IBA 06/2021
1	Group II Phospholipases A2IBA 06/2021
1	Phospholipases (Phospholipase)IBA 06/2021
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 06/2021
1	Histones (Histone)IBA 02/2021
1	Protein-Arginine DeiminasesIBA 02/2021
1	Protons (Proton)IBA 01/2021
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2021
1	FluoroquinolonesIBA 01/2021
1	Branched-Chain Amino AcidsIBA 01/2021
1	Vitamin K FDA Link 01/2021
1	Complement C3 (C3 Complement)IBA 08/2020
1	Therapeutic UsesIBA 01/2020
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2019
1	allysineIBA 01/2019
1	Troponin T (Troponin T1)IBA 01/2019
1	Fibrinopeptide AIBA 01/2019
1	Methanol (Carbinol)IBA 12/2018
1	Chloroform (Trichloromethane)IBA 12/2018
1	Nonesterified Fatty Acids (NEFA)IBA 01/2018
1	Dacarbazine (DIC)FDA LinkGeneric 01/2018
1	PhosphatidylserinesIBA 01/2018
1	acylcarnitineIBA 01/2018
1	Hemostatics (Antihemorrhagics)IBA 12/2017
1	CytokinesIBA 11/2017
1	Biological ProductsIBA 09/2017
1	Syndecan-1 (Syndecan 1)IBA 12/2016

Therapy/Procedure

35	Resuscitation 01/2021 - 01/2004
18	Therapeutics 09/2017 - 08/2005
8	Early Goal-Directed Therapy 01/2016 - 08/2007
5	Induced Hypothermia 01/2019 - 12/2008
3	Precision Medicine 01/2020 - 01/2015
3	Length of Stay 03/2014 - 11/2004
3	Airway Management 11/2013 - 08/2012
2	Cardiopulmonary Resuscitation (CPR) 06/2010 - 04/2008
1	Long-Term Care 01/2021
1	Fluid Therapy (Oral Rehydration Therapy) 10/2018
1	Lasers (Laser) 07/2016